Personal Details
Education
October 1998 to July 2005: |
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Study of MSc. in Computer Science with
minor subject Medical Science
at the Friedrich-Schiller-University in
Jena, Germany
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December 2004 to June 2005: |
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Preparation of MSc. Thesis "Analysis and Design of GPU-based Algorithms
for Interactive Volume Segmentation" at the University of Auckland, New Zealand
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Taken Computer Science courses including:
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Object Oriented Analysis and Design, Software Development Techniques
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Pattern Recognition, Digital Image Processing, 3D Computer Vision
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Computational Geometry, Parallel Computing
Taken Medical courses:
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Medical Imaging Techniques (X-Ray, MRT, CT, UltraSound, PET,...)
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Image Processing Methods for Medical Diagnosis
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Radiological Treatment
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Basic courses in Pathophysiology, Physiology, Anatomy
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February 2001: |
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Associate Degree in Computer
Science from the Friedrich-Schiller-University
in Jena, Germany
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Work Experience
November 2005 to April 2007: |
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Research Associate at the Department for Experimental
Ophthalmology at the Friedrich-Schiller-University, Jena, Germany.
In this project an industrial Laser Scanning Ophthalmoscope has been advanced to
allow for 2-dimensional Fluorescence Lifetime Imaging (FLIM)
at the human ocular fundus. The method of Time Correlated Single Photon Counting
is used in conjunction with a sensitive detector to determine the decay-times of the natural
fluorophores. The aim of this project is to measure certain parameters of
metabolism in the retinal tissue and detect diseases like age-related macula
degeneration (AMD), diabetic retinopathy or glaucoma before pathological
changes are manifest.
Please see publications for further details.
Main achievements in this research group:
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Design and implementation of a multithreaded, synchronized device-control, realtime data acquisition and
alignment software; as plugin for vendor specific software-suite
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Contribution to measurement system arrangement and improvement
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Design of a Data Analysis and Visualization Tool for the spatial- and time-resolved multiexponential measurement data
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Development of an Image Registration Tool using the ITK-Library
Head of Research Group: HDoz. Dr.-Ing. habil. Dietrich Schweitzer
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December 2004 to June 2005: |
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Preparation of MSc. Thesis "Analysis and Design of GPU-based Algorithms
for Interactive Volume Segmentation" at the University of Auckland, New Zealand
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Design and implementation of GPU-based 3D image processing techniques, including:
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Mean- and anisotropic diffusion filter for image enhancement
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Threshold-based segmentation and seeding
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3D morphological seed manipulation
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3D theshold-based and anisotropic diffusion-based seeded region growing segmentation
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Integration as a plugin into the Visualization Toolkit architecture
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Development of an application providing
- im/export of 3D datasets
- GUI for interactive control of filter\segmentation process
- basic volume rendering / slice viewing using VTK visualization functionality
Supervised by Prof. Denzler and Burkhard Wünsche, PhD
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May 2004 to October 2004: |
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Part-time based work in the Software Engineering Department
of Carl Zeiss Meditec in Jena, Germany.
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Design, implementation and test of a Windows Driver Model (WDM) device driver
for an ophthalmic
Fundus Camera under Windows XP
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Contribution to technical project documentation
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March 2002 to July 2004: |
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Collaboration in a research project at the Department for Experimental
Ophthalmology at the Friedrich-Schiller-University, Jena, Germany.
In this project a Confocal Laser Scanning Ophthalmoscope has been advanced to
measure the 2-dimensional time-resolved autofluorescence of the ocular fundus.
The method of Time Correlated Single Photon Counting is used in conjunction
with a sensitive detector to determine the decay-times of the natural
fluorophores. The aim of this project is to measure certain parameters of
metabolism in the retinal tissue and detect diseases like age-related macula
degeneration (AMD), diabetic retinopathy or glaucoma before pathological
changes are manifest. This research project is partially funded by the
Federal Ministry for Education and Research.
I have contributed to the development of a measurement-technique which led to
the application of a patent. Please see
publication-section for further details and achievements.
My assignment was the development of the measurement software "EyeScan" with
the following features:
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control of the measurement sequence
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streaming of continuous video images of reflected light from the Confocal Laser
Scanning Ophthalmoscope in real-time
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adjustment of the control-parameters of a special
Time-Correlated-Single-Photon-Counting PCI device to detect
fluorescence-photons
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triggers synchronized measurements of a framegrabber and the TCSPC-device
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visualization of the collected 2-dimensional autofluorescence distribution of
the fundus in pseudo-color which can be interactively adjusted
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automatical detection of eye-movements between different measurements by
image-registration techniques
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merge of several shift corrected measurements to increase the number of
detected photons per pixel
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visualization of the decay versus time curve for every pixel of the
fluorescence image at the mouse-cursor
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storage of the acquired reflection- and fluorescence-data in a specific
fileformat
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export of fluorescence-decay-data for further analysis
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provides an easy to use graphical user interface
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uses DirectDraw to increase performance
Supervised by HDoz. Dr.-Ing. habil. Dietrich Schweitzer
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September 2003 to January 2004: |
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Development of the software VesselO2 for a research
project at the Department for Experimental Ophthalmology at
the Friedrich-Schiller-University, Jena, Germany. It is used to compute the
oxygen saturation in the retina from images taken by a fundus camera at
different wavelengths of the reflected light.
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reads a set of fundus camera images at different wavelengths
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performs several image processing techniques to detect the location and
expansion of retinal blood vessels
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computes the 2-dimensional local distribution of the oxygen saturation in
vessel areas as well as the ocular fundus itself
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visualizes the oxygen saturation with a pseudocolor technique which the user
can interactively adjust
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allows export of computed saturation data to an ASCII-file format to easily
enable further processing in other applications
Under direction by HDoz. Dr.-Ing. habil. Dietrich Schweitzer
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March to June 2002: |
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Development of the medical data-acquisition and
-visualization software "Liquo" in conjunction with the MD thesis of a medical
science student at the Department of Anesthesiology and Intensive Care Medicine
of the Friedrich-Schiller-University, Jena, Germany.
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receives real-time data from an arterial and central-venous-catheter based physiological monitor
system
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performs pulse-contour analysis on the blood-pressure curve to detect systoles
and computes the systolic-pressure-variation, a new technique for clinical
assessment of cardiac preload and volume responsiveness which was the subject
of the PhD thesis
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visualizes a detailed blood-pressure curve with a trend-curve as well as other
physiological hemodynamic variables like current heart rate, systolic and
diastolic arterial blood pressure
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streams the received data to a file and offers export of relevant data to Excel
compatible files
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has successfully been used during major surgery and proved clinical relevance
of the concept of systolic-pressure-variation
Supervised by Samir Sakka, MD, PhD
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August to October 2001: |
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Internship at Vulpine 3D Technologies GmbH
which evolved to Trinigy GmbH, Reutlingen, Germany.
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Conception, development and examination of automated test processes for the
Vulpine Vision 3D Engine
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Generation and tweaking of shaders within the Vulpine ShaderTool
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Collaboration on the implementation of constructive solid geometry functions
within Vulpine proprietary tools
References provided on request
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May 1998 to June 2001: |
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Student Assistant at the Fraunhofer Institute
for Applied Optics and Precision Engineering, Jena, Germany.
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Development of a highspeed projection system for an optical 3D-Scanning-System
using DirectDraw
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Maintenance of the code of a configuration program of the optical
3D-Scanning-System
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Programming a microcontroller for an underwater transmissiometer built for
environmental investigations, which controls the electronic parts inside and
communicates (receiving commands as well as transferring measured data) with an
user above the water surface
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Programming "VisualBasic for Applications"-macros for Excel to process the
acquired data and storing it via ODBC in an Oracle database
References provided on request
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Referees
Publications
Publications
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In vivo autofluorescence lifetime imaging at the fundus of the human eye
Dietrich Schweitzer, Martin Hammer, Frank Schweitzer, Stefan Schenke, Eckhard Birckner, Wolfgang Becker, Axel Bergmann
Proceedings of SPIE Vol. 6138 (2006) 613808-1 – 613808-10
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GPU-Based Volume Segmentation
Stefan Schenke and Burkhard C. Wünsche
Image and Vision Computing New Zealand, Dunedin, 28.-29. November 2005
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Comparison of time-resolved autofluorescence in the eye-ground of healthy subjects and patients suffering from age-related macula degeneration
D. Schweitzer, F. Schweitzer, M. Hammer, S. Schenke, S. Richter
Progress in Biomedical Optics and Imaging, Vol. 6, No. 31, SPIE 5862, 58620 R-1 – 58620 R-12, 2005
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Time-Resolved Autofluorescence Yields More Information Than Intensity Measurements of Fundus Autofluorescence
D. Schweitzer, F. Schweitzer, M. Hammer, S. Schenke, S. Richter
Invest. Ophthalmol. Vis. Sci. 46: E-Abstract 227, 2005
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In vivo measurement of time-resolved autofluorescence at the human ocular fundus
D. Schweitzer, M. Hammer, F. Schweitzer, R. Anders, T. Doebbecke, S. Schenke, E. R. Gaillard
Journal of Biomedical Optics, Vol. 9 No. 6 pp 1214-1222, 2004
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Veränderungen der Autofluoreszenzlebensdauer am Fundus
nach Sauerstoffprovokation
(Alteration of autofluorescence decay time in the fundus after breathing 100%
oxygen)
Schweitzer D., Hammer M., Anders R., Doebbecke T., Schenke S.
Ophthalmologe 2004, 101:66-72
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Metabolic mapping by time-resolved autofluorescence
Schweitzer D., Hammer M., Schenke S., Anders R.
European Journal of Ophthalmology Vol. 13 No. 2, 2003, p 230
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Evaluation of time-resolved autofluorescence images of
the ocular fundus
Schweitzer D., Hammer M., Schweitzer F., Schenke S., Gaillard E.R.
Proceedings of SPIE 5141 "Diagnostic Optical Spectroscopy in Biomedicine II"
ed. by G.A. Wagnieres, 2003 pp 8-17
Talks
- Steuerung der intraoperativen Volumentherapie an Hand der systolischen Druckvariation: Gibt es Vorteile hinsichtlich der Organfunktionen?
M. Büttner, S. Schenke, O. Thümer, W. Schummer, S. G. Sakka
Deutscher Anästhesiecongress, München, 16.–19. April 2005
- Systolic pressure variation guided volume therapy – are there any advantages in organ function?
O. Thümer, M. Büttner, S. Schenke, W. Schummer, S. G. Sakka
European Society of Intensive Care Medicine - 18th Annual Congress, Amsterdam, 25.–28. September 2005
- Comparison of time-resolved autofluorescence in the eye-ground of healthy subjects and patients suffering from age-related macular degeneration
D. Schweitzer, F. Schweitzer, M. Hammer, S. Schenke, S. Richter
European Conference on Biomedical Optics, München, Mai 2005-10-04
- Interpretation der dynamischen Autofluoreszenz am Augenhintergrund
D. Schweitzer, F. Schweitzer, M. Hammer, S. Richter, S. Schenke
XIV. Workshop „Okuläre Mikrozirkulation“, Weimar, 26.–27. Februar 2005
- Diagnostische Möglichkeiten der zeitlich und spektral aufgelösten Autofluoreszenzbeobachtung bei alterbedingter Makuladegeneration
M. Hammer, D. Schweitzer, S. Richter, S. Schenke
13. Tagung der Gesellschaft der Augenärzte Sachsen-Anhalts und Thüringens, Jena, 12.–13. November 2004
- Erste Studienergebnisse zur Messung der 2-dimensional zeitaufgelösten Autofluoreszenz am Augenhintergrund
D. Schweitzer, F. Schweitzer, S. Schenke, M. Hammer, S. Richter
XIII Workshop „Okuläre Mikrozirkulation“, München, 28.–29. Februar 2004
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Evaluation of time-resolved autofluorescence images of the ocular fundus
Schweitzer D., Hammer M., Schweitzer F., Schenke S., Gaillard E.R.
European Conference on Biomedical Optics June, 22-25, 2003, Munich
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Metabolic mapping by time-resolved autofluorescence
Schweitzer D., Hammer M., Schenke S., Anders R.
International Workshop NTG & PEX, April 3-5, 2003, Erlangen, Germany
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Metabolic mapping by time-resolved autofluorescence
Schweitzer D., Hammer M., Schenke S., Anders R.
3. CAFIA meeting Computer Assisted Fundus Image Analysis, March 28-30, 2003,
Torino, Italy
- Änderung der zeitaufgelösten Autofluoreszenz nach Sauerstoffprovokation
D. Schweitzer, M. Hammer, S. Schenke, P. Gänßler
Workshop "Okuläre Mikro- und Makrozirkulation" Dresden, 28. Februar – 01. März 2003
Pending Patent
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Verfahren und Anordnung zur Gewinnung und Auswertung kontrastreicher
Bilder der zeitaufgelösten Fluoreszenz von bewegten Objekten, beispielsweise
des Augenhintergrundes
(Method and arrangement for acquisition and evaluation of contrast-rich images
of time-resolved fluorescence of moving objects, e.g. the ocular fundus)
Schweitzer D., Schweitzer F., Schenke S., Hammer M.
10. February 2004, Aktenzeichen 102004006960.3
Skills
Programming:
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Several years experience in Object Oriented Software Development in C/C++
using Microsoft Visual Studio .NET
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Developing Graphical / Image Processing Applications using
- The Visualization Toolkit (VTK)
- The Insight Toolkit (ITK)
- OpenGL
- High Level Shading Languages (GLSL, Cg)
- DirectX, esp. Direct3D, DirectDraw
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GPGPU-Development
Implementing Image Processing Tasks on GPUs
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Knowledge of Win32-API including
GUI / Controls / Windowing / GDI / GDI+ / Multithreading
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Basic knowledge in Matlab, JAVA, PASCAL, VisualBasic, HTML 4.0, CSS
General:
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MS Windows XP, 2000, 98
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MS Office including database design and VBA-macro-programming in MS Access
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basic Unix/Linux
Personal:
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ability to work in a team environment as well as self-dependent
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research experience
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working reliably and precisely
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ability to learn quickly new methods and techniques
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being versatile and flexible
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